BDBM50042501 6-Benzyloxy-2H-chromene-3-carboxylic acid hydroxy-methyl-amide::CHEMBL118212

SMILES CN(O)C(=O)C1=Cc2cc(OCc3ccccc3)ccc2OC1

InChI Key InChIKey=UTPKHPOITVMUBJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50042501   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50042501(6-Benzyloxy-2H-chromene-3-carboxylic acid hydroxy-...)
Affinity DataIC50: 100nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase by reduction of 5-hydroxyeicosatetraenoic acid (5-HETE) formed in guinea pig polymorphonuclear le...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50042501(6-Benzyloxy-2H-chromene-3-carboxylic acid hydroxy-...)
Affinity DataIC50: 61nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase by reduction of LTB4 formed in guinea pig polymorphonuclear leukocytes (PMNs).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed