BDBM50042250 4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL444060
SMILES CCCCC1NC(=O)C2(CCCC2)N1Cc1ccc(cc1)-c1ccccc1C(O)=O
InChI Key InChIKey=ILERVMNMFVURPH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50042250
Affinity DataIC50: 3.30E+3nMAssay Description:Binding affinity for Angiotensin II receptor, type 1 measured by ability to displace [125I]- A II from its specific binding site in rat liver membran...More data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 2(Human)
Fraunhofer Institute For Translational Medicine and Phamacology Itmp
Curated by ChEMBL
Fraunhofer Institute For Translational Medicine and Phamacology Itmp
Curated by ChEMBL
Affinity DataEC50: 2.42E+4nMAssay Description:Agonist activity at human BLT2 overexpressed in CHO-K1 cells assessed as accumulation of inositol monophosphate measured after 90 mins by HTRF assayMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor(Human)
Fraunhofer Institute For Translational Medicine and Phamacology Itmp
Curated by ChEMBL
Fraunhofer Institute For Translational Medicine and Phamacology Itmp
Curated by ChEMBL
Affinity DataIC50: 7.75E+3nMAssay Description:Antagonist activity at human AT1 overexpressed in CHO-K1 cells in presence of 10 nM [Val5-angiotensin II measured after 90 mins by HTRF based IP-one ...More data for this Ligand-Target Pair