BDBM50042116 1-(2,6-Diisopropyl-phenyl)-3-(1,2,3,4-tetrahydro-naphthalen-2-yl)-urea::CHEMBL73336

SMILES CC(C)c1cccc(C(C)C)c1NC(=O)NC1CCc2ccccc2C1

InChI Key InChIKey=KWWJFTXMFCYMHF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50042116   

TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50042116(1-(2,6-Diisopropyl-phenyl)-3-(1,2,3,4-tetrahydro-n...)
Affinity DataIC50: 63nMAssay Description:In vitro inhibitory activity against ACAT was determined in rabbit intestinal microsome from cholesterol-fed animalsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50042116(1-(2,6-Diisopropyl-phenyl)-3-(1,2,3,4-tetrahydro-n...)
Affinity DataIC50: 41nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbitsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed