BDBM50041943 6-(2,5-Dimethoxy-benzyl)-5-methyl-thieno[2,3-d]pyrimidine-2,4-diamine::6-(2,5-dimethoxybenzyl)-5-methylthieno[2,3-d]pyrimidine-2,4-diamine::CHEMBL104787

SMILES COc1ccc(OC)c(Cc2sc3nc(N)nc(N)c3c2C)c1

InChI Key InChIKey=WVIZZYJRTWDOHO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50041943   

TargetDihydrofolate reductase(Escherichia coli (strain K12))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041943(6-(2,5-dimethoxybenzyl)-5-methylthieno[2,3-d]pyrim...)
Affinity DataIC50: 70nMAssay Description:Inhibition of dihydrofolate reductase in Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041943(6-(2,5-dimethoxybenzyl)-5-methylthieno[2,3-d]pyrim...)
Affinity DataIC50: 730nMAssay Description:Tested for inhibitory activity against dihydrofolate reductase in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041943(6-(2,5-dimethoxybenzyl)-5-methylthieno[2,3-d]pyrim...)
Affinity DataIC50: 400nMAssay Description:Inhibition of rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50041943(6-(2,5-dimethoxybenzyl)-5-methylthieno[2,3-d]pyrim...)
Affinity DataIC50: 70nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041943(6-(2,5-dimethoxybenzyl)-5-methylthieno[2,3-d]pyrim...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of dihydrofolate reductase in pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed