BDBM50041929 6-(2,5-Dimethoxy-phenyl)-5-methyl-thieno[2,3-d]pyrimidine-2,4-diamine::6-(2,5-dimethoxyphenyl)-5-methylthieno[2,3-d]pyrimidine-2,4-diamine::CHEMBL323960

SMILES COc1ccc(OC)c(c1)-c1sc2nc(N)nc(N)c2c1C

InChI Key InChIKey=HZLAEKPBPKLCAR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50041929   

TargetDihydrofolate reductase(Escherichia coli (strain K12))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041929(6-(2,5-Dimethoxy-phenyl)-5-methyl-thieno[2,3-d]pyr...)
Affinity DataIC50: 130nMAssay Description:Inhibition of dihydrofolate reductase in Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041929(6-(2,5-Dimethoxy-phenyl)-5-methyl-thieno[2,3-d]pyr...)
Affinity DataIC50: 750nMAssay Description:Tested for inhibitory activity against dihydrofolate reductase in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041929(6-(2,5-Dimethoxy-phenyl)-5-methyl-thieno[2,3-d]pyr...)
Affinity DataIC50: 370nMAssay Description:Inhibition of rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041929(6-(2,5-Dimethoxy-phenyl)-5-methyl-thieno[2,3-d]pyr...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of dihydrofolate reductase in pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed