BDBM50041468 7-Chloro-4-hydroxy-3-(3-thiophen-3-ylmethyl-phenyl)-1H-quinolin-2-one::CHEMBL280853

SMILES Oc1c(-c2cccc(Cc3ccsc3)c2)c(=O)[nH]c2cc(Cl)ccc12

InChI Key InChIKey=UACGCNCLAOPGCQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50041468   

TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50041468(7-Chloro-4-hydroxy-3-(3-thiophen-3-ylmethyl-phenyl...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of the binding of [3H]L-689,560 ([3H]-4) to the strychnine-insensitive glycine site on rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed