BDBM50041466 7-Chloro-4-hydroxy-3-[3-(4-methoxymethoxy-benzyl)-phenyl]-1H-quinolin-2-one::CHEMBL31718

SMILES COCOc1ccc(Cc2cccc(c2)-c2c(O)c3ccc(Cl)cc3[nH]c2=O)cc1

InChI Key InChIKey=JNVNXHMNESKCEC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50041466   

TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50041466(7-Chloro-4-hydroxy-3-[3-(4-methoxymethoxy-benzyl)-...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of the binding of [3H]L-689,560 ([3H]-4) to the strychnine-insensitive glycine site on rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed