BDBM500414 4-(7- methylimidazo [1,2-a]pyridin- 3-yl)-7-[[5-(4- methylpiperazin- 1-yl)-2-pyridyl]- amino]-2,3- dihydropyrrolo [3,4-c]pyridin-1-::US11021481, Compound I-73::US11078201, Compound I-73::US11548890, Compound I-73

SMILES CN1CCN(CC1)c1ccc(Nc2cnc(c3CNC(=O)c23)-c2cnc3cc(C)ccn23)nc1

InChI Key InChIKey=XPONBIJYOLPDHB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 500414   

LigandPNGBDBM500414(US11021481, Compound I-73 | 4-(7- methylimidazo [1...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
Go to US Patent

LigandPNGBDBM500414(US11021481, Compound I-73 | 4-(7- methylimidazo [1...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
Go to US Patent

LigandPNGBDBM500414(US11021481, Compound I-73 | 4-(7- methylimidazo [1...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
Go to US Patent

LigandPNGBDBM500414(US11021481, Compound I-73 | 4-(7- methylimidazo [1...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
Go to US Patent