BDBM50041368 (S)-6-Ethynyl-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione::CHEMBL25700

SMILES CC12CCC3C(C[C@@H](C#C)C4=CC(=O)CCC34C)C1CCC2=O

InChI Key InChIKey=JTFYIUMDFFPNCQ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50041368   

TargetAromatase(Human)
Tohoku College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041368((S)-6-Ethynyl-10,13-dimethyl-1,6,7,8,9,10,11,12,13...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibitory concentration was tested on Cytochrome P450 19A1 in human placental microsomes 20 (microg) of protein incubated for 20 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041368((S)-6-Ethynyl-10,13-dimethyl-1,6,7,8,9,10,11,12,13...)
Affinity DataKi:  62nMAssay Description:Binding affinity for human placental microsome Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed