BDBM50041300 1-(8-Methyl-3-naphthalen-1-yl-8-aza-bicyclo[3.2.1]oct-2-yl)-propan-1-one::CHEMBL278572

SMILES CCC(=O)C1C2CCC(CC1c1cccc3ccccc13)N2C

InChI Key

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50041300   

TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50041300(1-(8-Methyl-3-naphthalen-1-yl-8-aza-bicyclo[3.2.1]...)
Affinity DataIC50: 5.30nMAssay Description:Inhibitory activity in displacing [125I]- RTI-55 binding to dopamine transporter in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50041300(1-(8-Methyl-3-naphthalen-1-yl-8-aza-bicyclo[3.2.1]...)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50041300(1-(8-Methyl-3-naphthalen-1-yl-8-aza-bicyclo[3.2.1]...)
Affinity DataKi:  21nMAssay Description:Affinity for the displacement of [3H]paroxetine binding to serotonin transporter (SERT) in rat frontal cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50041300(1-(8-Methyl-3-naphthalen-1-yl-8-aza-bicyclo[3.2.1]...)
Affinity DataKi:  21nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50041300(1-(8-Methyl-3-naphthalen-1-yl-8-aza-bicyclo[3.2.1]...)
Affinity DataKi:  49nMAssay Description:Affinity for the displacement of [3H]paroxetine binding to norepinephrine transporter (NET) in rat frontal cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed