BDBM500413 4-(7-methylimidazo [1,2-a]pyridin- 3-yl)-7-[(5- piperazin-1-yl- 2-pyridyl)amino] isoindolin-1-one::US11021481, Compound I-72::US11021481, Compound I-89::US11078201, Compound I-72::US11548890, Compound I-72

SMILES Cc1ccn2c(cnc2c1)-c1ccc(Nc2ccc(cn2)N2CCNCC2)c2C(=O)NCc12

InChI Key InChIKey=CAZFTECNXBMSLF-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 500413   

LigandPNGBDBM500413(4-(7-methylimidazo [1,2-a]pyridin- 3-yl)-7-[(5- pi...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
Go to US Patent

LigandPNGBDBM500413(4-(7-methylimidazo [1,2-a]pyridin- 3-yl)-7-[(5- pi...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
Go to US Patent

LigandPNGBDBM500413(4-(7-methylimidazo [1,2-a]pyridin- 3-yl)-7-[(5- pi...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
Go to US Patent

LigandPNGBDBM500413(4-(7-methylimidazo [1,2-a]pyridin- 3-yl)-7-[(5- pi...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
Go to US Patent

LigandPNGBDBM500413(4-(7-methylimidazo [1,2-a]pyridin- 3-yl)-7-[(5- pi...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
Go to US Patent

LigandPNGBDBM500413(4-(7-methylimidazo [1,2-a]pyridin- 3-yl)-7-[(5- pi...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
Go to US Patent