BDBM50041218 3-(7-Carbamimidoyl-naphthalen-2-yl)-2-{4-[(S)-1-(1-imino-ethyl)-pyrrolidin-3-yloxy]-phenyl}-propionic acid::CHEMBL19660

SMILES CC(=N)N1CC[C@@H](C1)Oc1ccc(cc1)C(Cc1ccc2ccc(cc2c1)C(N)=N)C(O)=O

InChI Key InChIKey=AGRCGQSFFMCBRE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50041218   

TargetCoagulation factor X(Human)
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041218(CHEMBL19660 | 3-(7-Carbamimidoyl-naphthalen-2-yl)-...)
Affinity DataIC50: 160nMAssay Description:In vitro evaluation for the concentration needed for inhibiting factor Xa by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041218(CHEMBL19660 | 3-(7-Carbamimidoyl-naphthalen-2-yl)-...)
Affinity DataIC50: 1.20E+6nMAssay Description:In vitro evaluation for the concentration needed for inhibiting thrombin by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041218(CHEMBL19660 | 3-(7-Carbamimidoyl-naphthalen-2-yl)-...)
Affinity DataIC50: 60nMAssay Description:Inhibitory concentration against human Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041218(CHEMBL19660 | 3-(7-Carbamimidoyl-naphthalen-2-yl)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Coagulation factor IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed