BDBM50041127 6-Thiophen-2-yl-5H-[1,3]dioxolo[4,5-g]quinolin-8-one::CHEMBL14540

SMILES Oc1cc(nc2cc3OCOc3cc12)-c1cccs1

InChI Key InChIKey=NMFTWAYYGHNSDJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50041127   

TargetTubulin beta-2B chain(Bovine)
School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041127(6-Thiophen-2-yl-5H-[1,3]dioxolo[4,5-g]quinolin-8-o...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50041127(6-Thiophen-2-yl-5H-[1,3]dioxolo[4,5-g]quinolin-8-o...)
Affinity DataIC50: 2.19E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed