BDBM500411 7-[[5-(3,8- diazabicyc1o [3,2.1]octan- 3-yl)-2- pyridyl]amino]- 4-(1-methylpyrrolo [2,3-b]pyridin- 4-yl)isoindolin- 1-one::US11021481, Compound I-70::US11078201, Compound I-70::US11548890, Compound I-70

SMILES Cn1ccc2c(ccnc12)-c1ccc(Nc2ccc(cn2)N2CC3CCC(C2)N3)c2C(=O)NCc12

InChI Key InChIKey=ALKMCFYWGZISEE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 500411   

LigandPNGBDBM500411(US11021481, Compound I-70 | 7-[[5-(3,8- diazabicyc...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
Go to US Patent

LigandPNGBDBM500411(US11021481, Compound I-70 | 7-[[5-(3,8- diazabicyc...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
Go to US Patent

LigandPNGBDBM500411(US11021481, Compound I-70 | 7-[[5-(3,8- diazabicyc...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
Go to US Patent

LigandPNGBDBM500411(US11021481, Compound I-70 | 7-[[5-(3,8- diazabicyc...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
Go to US Patent

LigandPNGBDBM500411(US11021481, Compound I-70 | 7-[[5-(3,8- diazabicyc...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
Go to US Patent