BDBM50040468 2,6-Bis(1-methylethyl)phenyl[[2,6-Bis(1-methylethyl)phenoxy]sulfonyl]carbamate,Monosodium salt::Acylphosphoramidate analogue::CHEMBL25110::Sodium salt of 2,6-bis(1-methylethyl)phenyl[[2,6-bis(1-methyl)phenoxy]-sulfonyl]carbamate::Sodium salt of CarboSulfamic acid Bis-(2,6-diisopropyl-phenyl ester)::sodium salt of 2,6-isopropylphenylcraboxy-sulfamic acid 2,6-diisopropyl-phenyl ester::sodium salt of Acyl Sulfamate derivatives

SMILES CC(C)c1cccc(C(C)C)c1OC(=O)[N-]S(=O)(=O)Oc1c(cccc1C(C)C)C(C)C

InChI Key InChIKey=MHCQGCLTFBMETG-UHFFFAOYSA-M

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50040468   

TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50040468(Sodium salt of CarboSulfamic acid Bis-(2,6-diisopr...)
Affinity DataIC50: 5.20E+3nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50040468(Sodium salt of CarboSulfamic acid Bis-(2,6-diisopr...)
Affinity DataIC50: 4.00E+3nMAssay Description:In vitro inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase (ACAT) in rabbit intestinal microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50040468(Sodium salt of CarboSulfamic acid Bis-(2,6-diisopr...)
Affinity DataIC50: 5.30E+3nMAssay Description:Compound was evaluated for the Acyl coenzyme A:cholesterol acyltransferase inhibition using microsomes isolated from the livers of cholesterol fed ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50040468(Sodium salt of CarboSulfamic acid Bis-(2,6-diisopr...)
Affinity DataIC50: 5.30E+3nMAssay Description:Compound at 5 uM concentration was tested in vitro for inhibition of Acyl-CoA: Cholesterol Acyltransferase (ACAT) in liver microsomes of cholesterol ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50040468(Sodium salt of CarboSulfamic acid Bis-(2,6-diisopr...)
Affinity DataIC50: 5.30E+3nMAssay Description:In vitro inhibitory activity against acyl coenzyme A:cholesterol acyltransferase 1 in microsomes of rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed