BDBM50040349 8-Amino-1,3-bis-cyclopropylmethyl-7-(toluene-4-sulfonyl)-3,7-dihydro-purine-2,6-dione::CHEMBL144341

SMILES Cc1ccc(cc1)S(=O)(=O)n1c(N)nc2n(CC3CC3)c(=O)n(CC3CC3)c(=O)c12

InChI Key InChIKey=BJYKOWSYXIUDNY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50040349   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040349(8-Amino-1,3-bis-cyclopropylmethyl-7-(toluene-4-sul...)
Affinity DataIC50: 1.20E+3nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040349(8-Amino-1,3-bis-cyclopropylmethyl-7-(toluene-4-sul...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of adenosine binding to A1 receptor of rat brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed