BDBM50040295 5-[(2,5-Dihydroxy-benzylidene)-amino]-2-hydroxy-benzoic acid::5-{[1-(2,5-Dihydroxy-phenyl)-meth-(E)-ylidene]-amino}-2-hydroxy-benzoic acid::CHEMBL316764

SMILES OC(=O)c1cc(ccc1O)\N=C\c1cc(O)ccc1O

InChI Key InChIKey=XGAACHAKZZGIBP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50040295   

TargetEpidermal growth factor receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50040295(5-{[1-(2,5-Dihydroxy-phenyl)-meth-(E)-ylidene]-ami...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of EGF-stimulated DNA synthesis in ER 22 (EGF-receptor expressing) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50040295(5-{[1-(2,5-Dihydroxy-phenyl)-meth-(E)-ylidene]-ami...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory potency against protein tyrosine kinase activity associated with EGFR was evaluated using ER 22 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50040295(5-{[1-(2,5-Dihydroxy-phenyl)-meth-(E)-ylidene]-ami...)
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibition of p56lck autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50040295(5-{[1-(2,5-Dihydroxy-phenyl)-meth-(E)-ylidene]-ami...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of EGF-dependent DNA synthesis in ER 22 cells incubated with [3H]TdRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed