BDBM50040100 CHEMBL3359443

SMILES Oc1ccc2[nH]cc(CCNC(=O)c3ccccc3O)c2c1

InChI Key InChIKey=VTTVOWODYFXGJO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50040100   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Roseman University of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50040100(CHEMBL3359443)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of human TRPV1 overexpressed in BEAS-2B cells assessed as calcium flux after 30 mins by Fluo-4 AM fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50040100(CHEMBL3359443)
Affinity DataIC50: 800nMAssay Description:Inhibition of human COX1 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate incubated for 10 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50040100(CHEMBL3359443)
Affinity DataIC50: 1.74E+3nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate incubated for 10 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed