BDBM50039995 CHEMBL98777::[(S)-1-(1-Ethylcarbamoyl-2-phenyl-ethylcarbamoyl)-3-methyl-butyl]-carbamic acid benzyl ester

SMILES CCNC(=O)C(Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1

InChI Key InChIKey=PNRWOFORTRJIMC-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50039995   

TargetCalpain-2 catalytic subunit(Human)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039995([(S)-1-(1-Ethylcarbamoyl-2-phenyl-ethylcarbamoyl)-...)
Affinity DataKi:  35nMAssay Description:Tested for inhibitory activity on human calpain 2 from placentaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Bovine)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039995([(S)-1-(1-Ethylcarbamoyl-2-phenyl-ethylcarbamoyl)-...)
Affinity DataKi:  40nMAssay Description:Tested for inhibitory activity on bovine calpain 2 from heartMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Human)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039995([(S)-1-(1-Ethylcarbamoyl-2-phenyl-ethylcarbamoyl)-...)
Affinity DataKi:  51nMAssay Description:Tested for inhibitory activity on porcine calpain 2 from kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039995([(S)-1-(1-Ethylcarbamoyl-2-phenyl-ethylcarbamoyl)-...)
Affinity DataKi:  74nMAssay Description:Tested for inhibitory activity on human calpain 1 from erythrocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039995([(S)-1-(1-Ethylcarbamoyl-2-phenyl-ethylcarbamoyl)-...)
Affinity DataKi:  89nMAssay Description:In vitro inhibition of porcine erythrocyte calpain 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039995([(S)-1-(1-Ethylcarbamoyl-2-phenyl-ethylcarbamoyl)-...)
Affinity DataKi:  89nMAssay Description:In vitro inhibition of porcine erythrocyte calpain 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed