BDBM50039971 CHEMBL3358339

SMILES CN1C=C(C=C(C1=O)Nc2ccc(cn2)C(=O)N3CCOCC3)c4cccc(c4CO)N5C=Cc6cc(cc(c6C5=O)F)N(C)C

InChI Key InChIKey=PCVMXQPADBQRFE-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50039971   

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50039971(CHEMBL3358339)
Affinity DataIC50: 40nMAssay Description:Inhibition of BTK in human whole blood assessed as decrease in CD69 positive cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)