BDBM50039915 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid octanoyl-amide::CHEMBL274712

SMILES CCCCCCCC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCCC)nn(-c3ccccc3C(F)(F)F)c2=O)cc1

InChI Key InChIKey=FEZRQMGQHANOOE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50039915   

TargetType-1 angiotensin II receptor(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50039915(4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5...)
Affinity DataIC50: 2.90nMAssay Description:Displacement of 125I[Sar,Ile] from rabbit aorta membrane Angiotensin II receptor type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetType-1 angiotensin II receptor(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50039915(4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5...)
Affinity DataIC50: 2.90nMAssay Description:In vitro inhibitory activity against angiotensin II rabbit aorta AT1 receptor using radioligand [125I]-Sar Ile-AIIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetType-2 angiotensin II receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039915(4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5...)
Affinity DataIC50: 450nMAssay Description:In vitro inhibitory activity against angiotensin II rat midbrain AT2 receptor using radioligand [125I]-Sar Ile-AIIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed