BDBM50039760 (-)-Trifluoro-methanesulfonic acid 3-(1-propyl-piperidin-3-yl)-phenyl ester::CHEMBL90359::Trifluoro-methanesulfonic acid 3-((S)-1-propyl-piperidin-3-yl)-phenyl ester

SMILES CCCN1CCC[C@H](C1)c1cccc(OS(=O)(=O)C(F)(F)F)c1

InChI Key InChIKey=VUEGBGWRCATKQZ-UHFFFAOYSA-N

Data  10 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50039760   

TargetSigma non-opioid intracellular receptor 1(Rat)
University of GöTeborg

Curated by ChEMBL
LigandPNGBDBM50039760(Trifluoro-methanesulfonic acid 3-((S)-1-propyl-pip...)
Affinity DataIC50: 32nMAssay Description:Binding effinity for sigma receptor using 2 nM of [3H]DTG as radioligand, in membranes from brain minus cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
University of GöTeborg

Curated by ChEMBL
LigandPNGBDBM50039760(Trifluoro-methanesulfonic acid 3-((S)-1-propyl-pip...)
Affinity DataKi:  40nMAssay Description:Evaluated for binding towards Dopamine receptor D2 using [3H]N-0437 as radioligand from rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50039760(Trifluoro-methanesulfonic acid 3-((S)-1-propyl-pip...)
Affinity DataKi:  48nMAssay Description:Affinity against recombinant dopamine receptor (DA) D2 expressed in CHO-K1 cells, using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
University of GöTeborg

Curated by ChEMBL
LigandPNGBDBM50039760(Trifluoro-methanesulfonic acid 3-((S)-1-propyl-pip...)
Affinity DataKi:  68nMAssay Description:Binding towards Dopamine receptor D3 expressed in CHO-K1 cells using [3H]spiperone More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
University of GöTeborg

Curated by ChEMBL
LigandPNGBDBM50039760(Trifluoro-methanesulfonic acid 3-((S)-1-propyl-pip...)
Affinity DataKi:  68nMAssay Description:Tested for in vitro binding affinity against cloned mammalian dopamine autoreceptor (DA) receptors expressed in CHO-K1 cells [3H]-spiperone as radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of GöTeborg

Curated by ChEMBL
LigandPNGBDBM50039760(Trifluoro-methanesulfonic acid 3-((S)-1-propyl-pip...)
Affinity DataKi:  135nMAssay Description:Evaluated for binding towards dopamine D2-receptor using [3H]N-0437 as radioligand from rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
University of GöTeborg

Curated by ChEMBL
LigandPNGBDBM50039760(Trifluoro-methanesulfonic acid 3-((S)-1-propyl-pip...)
Affinity DataKi:  180nMAssay Description:Evaluated for binding towards Dopamine receptor D2 using [3H]-spiperone as radioligand, in cloned mammalian receptors expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of GöTeborg

Curated by ChEMBL
LigandPNGBDBM50039760(Trifluoro-methanesulfonic acid 3-((S)-1-propyl-pip...)
Affinity DataKi:  408nMAssay Description:Tested for affinity against striatal dopamine autoreceptor (DA) D2 receptors using [3H]spiperone as radioligand in rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of GöTeborg

Curated by ChEMBL
LigandPNGBDBM50039760(Trifluoro-methanesulfonic acid 3-((S)-1-propyl-pip...)
Affinity DataKi:  410nMAssay Description:Binding towards Dopamine receptor D2 using [3H]spiperone from rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
University of GöTeborg

Curated by ChEMBL
LigandPNGBDBM50039760(Trifluoro-methanesulfonic acid 3-((S)-1-propyl-pip...)
Affinity DataKi: >933nMAssay Description:Binding towards dopamine receptor D4 expressed in CHO-K1 cells using [3H]spiperone More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50039760(Trifluoro-methanesulfonic acid 3-((S)-1-propyl-pip...)
Affinity DataKi:  1.53E+3nMAssay Description:Tested for affinity against 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT in homogenized rat brain tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed