BDBM50039573 2-[1-[1-amino-4-amino(imino)methylamino-(1S)-butylcarboxamidomethylcarboxamido]-2-carboxy-(1S)-ethylcarboxamido]-3-(1H-3-indolyl)-(2S)-propanoic acid::CHEMBL87188

SMILES N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O

InChI Key InChIKey=IACNLTVRZIHFQK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50039573   

TargetIntegrin alpha-5/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039573(2-[1-[1-amino-4-amino(imino)methylamino-(1S)-butyl...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human umbilical vein endothelial cell adhesion to fibronectinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039573(2-[1-[1-amino-4-amino(imino)methylamino-(1S)-butyl...)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of human umbilical vein endothelial cell adhesion to fibrinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039573(2-[1-[1-amino-4-amino(imino)methylamino-(1S)-butyl...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human umbilical vein endothelial cell adhesion to vitronectinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039573(2-[1-[1-amino-4-amino(imino)methylamino-(1S)-butyl...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of platelet aggregation as the concentration necessary to inhibit the change in light. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed