BDBM50039559 CHEMBL267803::[5-(2-Amino-6-oxo-1,6-dihydro-purin-9-yl)-pentyl]-phosphonic acid

SMILES Nc1nc2n(CCCCCP(O)(O)=O)cnc2c(=O)[nH]1

InChI Key InChIKey=ZQMIYPAADORARG-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50039559   

TargetPurine nucleoside phosphorylase(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50039559([5-(2-Amino-6-oxo-1,6-dihydro-purin-9-yl)-pentyl]-...)
Affinity DataKi:  170nMAssay Description:Tested for its ability to inhibit calf spleen purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50039559([5-(2-Amino-6-oxo-1,6-dihydro-purin-9-yl)-pentyl]-...)
Affinity DataKi:  170nMAssay Description:Inhibition of human erythrocytic PNP (purine nucleoside phosphorylase) in 1 mM phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50039559([5-(2-Amino-6-oxo-1,6-dihydro-purin-9-yl)-pentyl]-...)
Affinity DataKi:  500nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50039559([5-(2-Amino-6-oxo-1,6-dihydro-purin-9-yl)-pentyl]-...)
Affinity DataKi:  1.70E+5nMAssay Description:PNP activity in human RBCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed