BDBM50039245 CHEMBL309357::Dimethyl-[2-(1,7,7-trimethyl-2-phenyl-bicyclo[2.2.1]hept-2-yloxy)-ethyl]-amine

SMILES CN(C)CCOC1(CC2CCC1(C)C2(C)C)c1ccccc1

InChI Key

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50039245   

TargetSodium- and chloride-dependent betaine transporter(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039245(Dimethyl-[2-(1,7,7-trimethyl-2-phenyl-bicyclo[2.2....)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of human GABA transporter (hBGT-1) activity.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 3(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039245(Dimethyl-[2-(1,7,7-trimethyl-2-phenyl-bicyclo[2.2....)
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibitory activity against human sodium and chloride dependent GABA transporter 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039245(Dimethyl-[2-(1,7,7-trimethyl-2-phenyl-bicyclo[2.2....)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibitory activity against human GABA transporter-1 (hGAT1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 2(Rat)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039245(Dimethyl-[2-(1,7,7-trimethyl-2-phenyl-bicyclo[2.2....)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory activity against rat GABA transporter-2 (rGAT2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed