BDBM50039244 1-(2-Tritylsulfanyl-ethyl)-piperidine-3-carboxylic acid::CHEMBL308528

SMILES OC(=O)C1CCCN(CCSC(c2ccccc2)(c2ccccc2)c2ccccc2)C1

InChI Key InChIKey=JRHIZITXMGMVQP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50039244   

TargetSodium- and chloride-dependent GABA transporter 3(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039244(1-(2-Tritylsulfanyl-ethyl)-piperidine-3-carboxylic...)
Affinity DataIC50: 9.10E+4nMAssay Description:Inhibitory activity against human sodium and chloride dependent GABA transporter 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 2(Rat)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039244(1-(2-Tritylsulfanyl-ethyl)-piperidine-3-carboxylic...)
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibitory activity against rat GABA transporter-2 (rGAT2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039244(1-(2-Tritylsulfanyl-ethyl)-piperidine-3-carboxylic...)
Affinity DataIC50: 4.35E+5nMAssay Description:Inhibition of human GABA transporter (hBGT-1) activity.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039244(1-(2-Tritylsulfanyl-ethyl)-piperidine-3-carboxylic...)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibitory activity against human GABA transporter-1 (hGAT1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed