BDBM50039119 CHEMBL44919::N-(5-Carboxy-5-{4-[(2,4-diamino-pteridin-6-ylmethyl)-amino]-benzoylamino}-pentyl)-phthalamic acid

SMILES Nc1nc(N)c2nc(CNc3ccc(cc3)C(=O)NC(CCCCNC(=O)c3ccccc3C(O)=O)C(O)=O)cnc2n1

InChI Key InChIKey=LZWQNHLDOZAEHC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50039119   

TargetDihydrofolate reductase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50039119(N-(5-Carboxy-5-{4-[(2,4-diamino-pteridin-6-ylmethy...)
Affinity DataIC50: 11nMAssay Description:rested for inhibitory concentration against human dihydrofolate reductase(DHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed