BDBM50039118 CHEMBL42819::N-(3-Carboxy-3-{4-[(2,4-diamino-pteridin-6-ylmethyl)-amino]-benzoylamino}-propyl)-phthalamic acid

SMILES Nc1nc(N)c2nc(CNc3ccc(cc3)C(=O)NC(CCNC(=O)c3ccccc3C(O)=O)C(O)=O)cnc2n1

InChI Key InChIKey=SQZCKWVARMTPGH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50039118   

TargetDihydrofolate reductase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50039118(N-(3-Carboxy-3-{4-[(2,4-diamino-pteridin-6-ylmethy...)
Affinity DataIC50: 12nMAssay Description:Tested for inhibitory concentration against human dihydrofolate reductase(DHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed