BDBM50039117 CHEMBL309160::N-(4-Carboxy-4-{3,5-dichloro-4-[(2,4-diamino-pteridin-6-ylmethyl)-amino]-benzoylamino}-butyl)-phthalamic acid

SMILES Nc1nc(N)c2nc(CNc3c(Cl)cc(cc3Cl)C(=O)NC(CCCNC(=O)c3ccccc3C(O)=O)C(O)=O)cnc2n1

InChI Key InChIKey=WYEXLNALRGCGSR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50039117   

TargetDihydrofolate reductase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50039117(N-(4-Carboxy-4-{3,5-dichloro-4-[(2,4-diamino-pteri...)
Affinity DataIC50: 10nMAssay Description:Tested for inhibitory concentration against human dihydrofolate reductase(DHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed