BDBM50038851 2-[3-(trifluoromethyl)benzyl]-1H,2'H,5'H-spiro[isoquinoline-4,3'-pyrrolidine]-1,2',3,5'(2H)-tetrone::CHEMBL62478

SMILES FC(F)(F)c1cccc(CN2C(=O)c3ccccc3C3(CC(=O)NC3=O)C2=O)c1

InChI Key InChIKey=OOXQIXCAJIJFNF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50038851   

TargetAldo-keto reductase family 1 member B1 [K65Q](Bovine)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50038851(2-[3-(trifluoromethyl)benzyl]-1H,2'H,5'H-spiro[iso...)
Affinity DataIC50: 17nMAssay Description:In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed