BDBM50038841 2-(4-bromo-2-fluorobenzyl)-6-chloro-1H,2'H,5'H-spiro[isoquinoline-4,3'-pyrrolidine]-1,2',3,5'(2H)-tetrone::CHEMBL444040

SMILES Fc1cc(Br)ccc1CN1C(=O)c2ccc(Cl)cc2C2(CC(=O)NC2=O)C1=O

InChI Key InChIKey=FXHUBUFAQBUAEN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50038841   

TargetAldo-keto reductase family 1 member B1 [K65Q](Bovine)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50038841(2-(4-bromo-2-fluorobenzyl)-6-chloro-1H,2'H,5'H-spi...)
Affinity DataIC50: 30nMAssay Description:In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed