BDBM50038709 1-(4-Iodo-phenyl)-cyclopentanecarboxylic acid 2-(4-phenyl-piperidin-1-yl)-ethyl ester; hydrochloride::CHEMBL554628

SMILES Ic1ccc(cc1)C1(CCCC1)C(=O)OCCN1CCC(CC1)c1ccccc1

InChI Key InChIKey=HHWKRRPTCYPMFB-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50038709   

TargetSigma non-opioid intracellular receptor 1(Human)
Albany Molecular Research

Curated by ChEMBL
LigandPNGBDBM50038709(1-(4-Iodo-phenyl)-cyclopentanecarboxylic acid 2-(4...)
Affinity DataKi:  1.40nMAssay Description:Affinity at sigma-1 site by inhibition of [3H](+)-pentazocine (PENT) binding in guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Albany Molecular Research

Curated by ChEMBL
LigandPNGBDBM50038709(1-(4-Iodo-phenyl)-cyclopentanecarboxylic acid 2-(4...)
Affinity DataKi:  55nMAssay Description:Iodo derivative shows a potent sigma binding ligand, had some affinity for D2 site in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed