BDBM50038704 CHEMBL3354882

SMILES COc1cc2CCN(CCCCc3cn(-c4ccc(F)cc4)c4ccccc34)Cc2cc1OC

InChI Key InChIKey=GWGRBNDXZUZCBZ-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50038704   

TargetATP-dependent translocase ABCB1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50038704(CHEMBL3354882)
Affinity DataEC50:  210nMAssay Description:Activity at MDR1 (unknown origin) expressed in MDCK-MDR1 cells by Calcein-AM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Hunan University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50038704(CHEMBL3354882)
Affinity DataKi:  5.30nMAssay Description:Displacement of (+)-[3H]pentazocine from sigma1 receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Hunan University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50038704(CHEMBL3354882)
Affinity DataKi:  1.39E+3nMAssay Description:Displacement of [3H]-(+)-pentazocine from guinea pig brain sigma1 receptor by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Hunan University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50038704(CHEMBL3354882)
Affinity DataKi:  1.39E+3nMAssay Description:Displacement of (+)-[3H]-pentazocine from sigma1 recetor in guinea-pig brain membranes without cerebellum by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed