BDBM50038474 CHEMBL3354377

SMILES FC(F)(F)c1cc(NC(=O)Nc2cccc(Nc3ncccc3-c3ncnc4[nH]cnc34)c2)ccc1Cl

InChI Key InChIKey=OPIIBVGNKWURBU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50038474   

TargetSerine/threonine-protein kinase B-raf(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50038474(CHEMBL3354377)
Affinity DataIC50: 12nMAssay Description:Inhibition of human GST-tagged full length B-Raf V600E mutant (unknown origin) using His6-tagged full-length human MEK1 (K97R) substrate and [33P]-ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed