BDBM50038288 CHEMBL3359960

SMILES O=C(Cn1ccnc1)c1ccc(OCc2ccccc2)cc1

InChI Key InChIKey=UEGZYLZJTBGZHA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50038288   

TargetAromatase(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50038288(CHEMBL3359960)
Affinity DataIC50: 4.49E+3nMAssay Description:Inhibition of human placental microsomal CYP19 using [1beta-3H]androstenedione substrate pre-incubated for 5 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50038288(CHEMBL3359960)
Affinity DataIC50: 149nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh11B1 cells using [1,2-3H]-11-deoxycorticosterone substrate incubated for 25 mins by HPLC metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50038288(CHEMBL3359960)
Affinity DataIC50: 588nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh11B2 cells using [1,2-3H]-11-deoxycorticosterone substrate incubated for 25 mins by HPLC metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed