BDBM50038258 Acetic acid 9-methyl-5-phenyl-6-thia-10b-aza-benzo[e]azulen-4-yl ester::CHEMBL326066

SMILES CC(=O)OC1=C(Sc2ccc(C)cc2-n2cccc12)c1ccccc1

InChI Key InChIKey=AAHGDCOQBZOQPP-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50038258   

TargetTranslocator protein(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50038258(Acetic acid 9-methyl-5-phenyl-6-thia-10b-aza-benzo...)
Affinity DataIC50: 676nMAssay Description:Displacement of [3H]-PK 11195 from rat peripheral (mitochondrial) benzodiazepine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50038258(Acetic acid 9-methyl-5-phenyl-6-thia-10b-aza-benzo...)
Affinity DataIC50: 675nMAssay Description:Inhibition of binding of [3H]-PK 11195 to peripheral-type benzodiazepine receptor (PBR) from rat cortex homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50038258(Acetic acid 9-methyl-5-phenyl-6-thia-10b-aza-benzo...)
Affinity DataIC50: 675nMAssay Description:Displacement of [3H]-PK 11195 from rat peripheral (mitochondrial) benzodiazepine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50038258(Acetic acid 9-methyl-5-phenyl-6-thia-10b-aza-benzo...)
Affinity DataKi:  263nMAssay Description:Binding affinity against peripheral-type benzodiazepine receptor (PBR) from rat cortex homogenate using [3H]-PK 11195 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed