BDBM50038256 CHEMBL117589::Dimethyl-carbamic acid 7-chloro-5-phenyl-6-thia-10b-aza-benzo[e]azulen-4-yl ester

SMILES CN(C)C(=O)OC1=C(Sc2c(Cl)cccc2-n2cccc12)c1ccccc1

InChI Key InChIKey=VCZPXCAFIGMLIM-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50038256   

TargetTranslocator protein(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50038256(Dimethyl-carbamic acid 7-chloro-5-phenyl-6-thia-10...)
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]-PK 11195 from rat peripheral (mitochondrial) benzodiazepine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50038256(Dimethyl-carbamic acid 7-chloro-5-phenyl-6-thia-10...)
Affinity DataIC50: 4nMAssay Description:Inhibition of binding of [3H]-PK 11195 to peripheral-type benzodiazepine receptor (PBR) from rat cortex homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50038256(Dimethyl-carbamic acid 7-chloro-5-phenyl-6-thia-10...)
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]-PK 11195 from rat peripheral (mitochondrial) benzodiazepine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50038256(Dimethyl-carbamic acid 7-chloro-5-phenyl-6-thia-10...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity against peripheral-type benzodiazepine receptor (PBR) from rat cortex homogenate using [3H]-PK 11195 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50038256(Dimethyl-carbamic acid 7-chloro-5-phenyl-6-thia-10...)
Affinity DataKi:  2.5nMAssay Description:Displacement [3H]-PK 11195 from rat adrenal peripheral-type benzodiazepine receptor (PBR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50038256(Dimethyl-carbamic acid 7-chloro-5-phenyl-6-thia-10...)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]-Ro- 5-4864 from rat adrenal peripheral-type benzodiazepine receptor (PBR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed