BDBM50037643 3-(2,4-Difluoro-phenyl)-1-[5-(1,4-diphenyl-1H-imidazol-2-ylsulfanyl)-pentyl]-1-heptyl-urea::CHEMBL49367

SMILES CCCCCCCN(CCCCCSc1nc(cn1-c1ccccc1)-c1ccccc1)C(=O)Nc1ccc(F)cc1F

InChI Key InChIKey=LFWPWLRPDFFJNH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50037643   

TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037643(3-(2,4-Difluoro-phenyl)-1-[5-(1,4-diphenyl-1H-imid...)
Affinity DataIC50: 7.20E+3nMAssay Description:In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) in rat hepatic microsomes by using AIV assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details

TargetSterol O-acyltransferase 1(Mouse)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037643(3-(2,4-Difluoro-phenyl)-1-[5-(1,4-diphenyl-1H-imid...)
Affinity DataIC50: 6.02E+3nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell culture by using J774 assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details

TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037643(3-(2,4-Difluoro-phenyl)-1-[5-(1,4-diphenyl-1H-imid...)
Affinity DataIC50: 4.20E+4nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed