BDBM50037452 6-(3-Dimethylamino-phenyl)-5H-[1,3]dioxolo[4,5-g]quinolin-8-one::CHEMBL275872

SMILES CN(C)c1cccc(c1)-c1cc(O)c2cc3OCOc3cc2n1

InChI Key InChIKey=PMTYBDLJRSCTJI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50037452   

TargetTubulin beta-2B chain(Bovine)
School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50037452(6-(3-Dimethylamino-phenyl)-5H-[1,3]dioxolo[4,5-g]q...)
Affinity DataIC50: 700nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50037452(6-(3-Dimethylamino-phenyl)-5H-[1,3]dioxolo[4,5-g]q...)
Affinity DataIC50: 700nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed