BDBM500373 7-[[5-(4- methylpiperazin- 1-yl)-2- pyridyl]amino]- 4-(1H- pyrrolo[2,3- b]pyridin-4- yl)-isoindolin- 1-one::US11021481, Compound I-31::US11078201, Compound I-31::US11548890, Compound I-31

SMILES CN1CCN(CC1)c1ccc(Nc2ccc(c3CNC(=O)c23)-c2ccnc3[nH]ccc23)nc1

InChI Key InChIKey=BIIKJKDKESGXFC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 500373   

LigandPNGBDBM500373(US11021481, Compound I-31 | 7-[[5-(4- methylpipera...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
Go to US Patent

LigandPNGBDBM500373(US11021481, Compound I-31 | 7-[[5-(4- methylpipera...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
Go to US Patent

LigandPNGBDBM500373(US11021481, Compound I-31 | 7-[[5-(4- methylpipera...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
Go to US Patent

LigandPNGBDBM500373(US11021481, Compound I-31 | 7-[[5-(4- methylpipera...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
Go to US Patent

LigandPNGBDBM500373(US11021481, Compound I-31 | 7-[[5-(4- methylpipera...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
Go to US Patent