BDBM50037044 4-[(6-Hydroxy-4,5,7-trimethyl-benzothiazol-2-ylamino)-methyl]-benzenesulfonamide::CHEMBL318809

SMILES Cc1c(C)c2nc(NCc3ccc(cc3)S(N)(=O)=O)sc2c(C)c1O

InChI Key InChIKey=IKIAJUVGDUYASS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50037044   

TargetLeukotriene B4 receptor 1(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037044(4-[(6-Hydroxy-4,5,7-trimethyl-benzothiazol-2-ylami...)
Affinity DataIC50: 30nMAssay Description:Tested for inhibitory activity against leukotriene B4 (LTB4) receptor in human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
LigandPNGBDBM50037044(4-[(6-Hydroxy-4,5,7-trimethyl-benzothiazol-2-ylami...)
Affinity DataIC50: 210nMAssay Description:Tested for inhibitory activity against 5-lipoxygenase in microsome of RBL-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50037044(4-[(6-Hydroxy-4,5,7-trimethyl-benzothiazol-2-ylami...)
Affinity DataIC50: 230nMAssay Description:Inhibition constant against arachidonate 5-lipoxygenase More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed