BDBM50037043 2-Ethylamino-4,5-dimethyl-7-pyridin-3-ylmethyl-benzothiazol-6-ol::CHEMBL105386

SMILES CCNc1nc2c(C)c(C)c(O)c(Cc3cccnc3)c2s1

InChI Key InChIKey=GVICCSAPBVEDOP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50037043   

TargetThromboxane-A synthase(Rat)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037043(2-Ethylamino-4,5-dimethyl-7-pyridin-3-ylmethyl-ben...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037043(2-Ethylamino-4,5-dimethyl-7-pyridin-3-ylmethyl-ben...)
Affinity DataIC50: 810nMAssay Description:Tested for inhibitory activity against thromboxane A2 (TXA2) synthetase in microsome of human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
LigandPNGBDBM50037043(2-Ethylamino-4,5-dimethyl-7-pyridin-3-ylmethyl-ben...)
Affinity DataIC50: 270nMAssay Description:Tested for inhibitory activity against 5-lipoxygenase in microsome of RBL-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed