BDBM50036976 (2S,4S,5S)-5-{(S)-2-[(S)-1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)-2-oxo-ethylamino]-hexanoylamino}-6-cyclohexyl-4-hydroxy-2-isopropyl-hexanoic acid (2-pyridin-2-yl-ethyl)-amide::CHEMBL101075

SMILES CCCC[C@H](N[C@@H](Cc1ccccc1)C(=O)N1CCC(CC1)OCOC)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)C[C@@H](C(C)C)C(=O)NCCc1ccccn1

InChI Key InChIKey=RPQFOGSNYUPJAG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50036976   

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50036976((2S,4S,5S)-5-{(S)-2-[(S)-1-Benzyl-2-(4-methoxymeth...)
Affinity DataIC50: 510nMAssay Description:Tested in vitro for its ability to inhibit the ferret plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50036976((2S,4S,5S)-5-{(S)-2-[(S)-1-Benzyl-2-(4-methoxymeth...)
Affinity DataIC50: 33nMAssay Description:Tested in vitro for its ability to inhibit the dog plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50036976((2S,4S,5S)-5-{(S)-2-[(S)-1-Benzyl-2-(4-methoxymeth...)
Affinity DataIC50: 9.40nMAssay Description:Tested in vitro for its ability to inhibit the human plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50036976((2S,4S,5S)-5-{(S)-2-[(S)-1-Benzyl-2-(4-methoxymeth...)
Affinity DataIC50: 7.00E+3nMAssay Description:Tested in vitro for its ability to inhibit the rat plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed