BDBM50036936 3'',4''-Dimethoxy-Aurone::3',4'-DIMETHOXY-AURONE::US11866416, Compound LC-I-197

SMILES COc1ccc(\C=C2/Oc3ccccc3C2=O)cc1OC

InChI Key InChIKey=FJYHPGCVLUAPLZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50036936   

TargetHistone deacetylase(Human)
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50036936(3'',4''-Dimethoxy-Aurone | 3',4'-DIMETHOXY-AURONE ...)
Affinity DataIC50: 7.10E+4nMAssay Description:Inhibition of HDAC in human HeLa cell extract after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 17B(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50036936(3'',4''-Dimethoxy-Aurone | 3',4'-DIMETHOXY-AURONE ...)
Affinity DataIC50: 2.14E+4nMAssay Description:Inhibition of recombinant GST-tagged DRAK2 (unknown origin) autophosphorylation after 2 hrs by ADP-glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2019
Entry Details Article
PubMed
TargetBiofilm regulatory protein A(Streptococcus mutans serotype c (strain ATCC 70061...)
Uab Research Foundation

US Patent
LigandPNGBDBM50036936(3'',4''-Dimethoxy-Aurone | 3',4'-DIMETHOXY-AURONE ...)
Affinity DataIC50: 8.40E+3nMAssay Description:A previously reported zymographic assay was utilized for the investigation of Gtf enzymatic activity, as described in Example 1. A 1:100 in fresh 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2024
Entry Details
Go to US Patent

TargetBiofilm regulatory protein A(Streptococcus mutans serotype c (strain ATCC 70061...)
Uab Research Foundation

US Patent
LigandPNGBDBM50036936(3'',4''-Dimethoxy-Aurone | 3',4'-DIMETHOXY-AURONE ...)
Affinity DataIC50: 8.40E+3nMAssay Description:A previously reported zymographic assay was utilized for the investigation of Gtf enzymatic activity, as described in Example 1. A 1:100 in fresh 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2024
Entry Details
Go to US Patent