BDBM50036868 2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl}-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo[d]isothiazol-3-one; compound with oxalic acid::CHEMBL51561

SMILES CCCN(CCCCN1C(=O)c2ccccc2S1(=O)=O)C1COc2cccc(OC)c2C1

InChI Key InChIKey=YPAYGSNPZFENEG-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50036868   

TargetAlpha-2A adrenergic receptor(Bovine)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50036868(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataIC50: 4.00E+4nMAssay Description:Binding affinity against alpha-2 adrenergic receptor in calf frontal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50036868(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataIC50: 1nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A (5-HT1A) receptor in rat hippocampus membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Bovine)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50036868(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor in calf frontal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Bovine)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50036868(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataIC50: 5.00E+4nMAssay Description:Binding affinity towards dopamine receptor D1 in calf striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50036868(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataIC50: 90nMAssay Description:Binding affinity against D2 receptor in calf caudate nucleusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50036868(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity for 5-hydroxytryptamine 1B receptor in rat cortex, striatum and globus pallidusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Bovine)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50036868(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against alpha-1 adrenergic receptor in calf frontal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
LigandPNGBDBM50036868(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:The compound was evaluated for its ability to displace [3H]ketanserin from 5-hydroxytryptamine 2 receptor in cellular brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details

LigandPNGBDBM50036868(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataIC50: 1nMAssay Description:The compound was evaluated for its ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in cellular brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details

LigandPNGBDBM50036868(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:The compound was evaluated for its ability to displace [3H]5-HT from 5-hydroxytryptamine 1B receptor in cellular brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details