BDBM50036863 CHEMBL51888::N-{2-[(5-Methoxy-chroman-3-yl)-propyl-amino]-ethyl}-4-methyl-benzenesulfonamide; compound with oxalic acid

SMILES CCCN(CCNS(=O)(=O)c1ccc(C)cc1)C1COc2cccc(OC)c2C1

InChI Key InChIKey=DKIWOYFHZPJYPI-UHFFFAOYSA-N

Data  1 KI  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50036863   

TargetAlpha-2A adrenergic receptor(Bovine)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50036863(N-{2-[(5-Methoxy-chroman-3-yl)-propyl-amino]-ethyl...)
Affinity DataIC50: 5.00E+4nMAssay Description:Binding affinity against alpha-2 adrenergic receptor in calf frontal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50036863(N-{2-[(5-Methoxy-chroman-3-yl)-propyl-amino]-ethyl...)
Affinity DataIC50: 1.00E+6nMAssay Description:Binding affinity for 5-hydroxytryptamine 1B receptor in rat cortex, striatum and globus pallidusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Bovine)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50036863(N-{2-[(5-Methoxy-chroman-3-yl)-propyl-amino]-ethyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor in calf frontal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50036863(N-{2-[(5-Methoxy-chroman-3-yl)-propyl-amino]-ethyl...)
Affinity DataIC50: 500nMAssay Description:Binding affinity against D2 receptor in calf caudate nucleusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Bovine)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50036863(N-{2-[(5-Methoxy-chroman-3-yl)-propyl-amino]-ethyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity against alpha-1 adrenergic receptor in calf frontal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50036863(N-{2-[(5-Methoxy-chroman-3-yl)-propyl-amino]-ethyl...)
Affinity DataIC50: 5nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A (5-HT1A) receptor in rat hippocampus membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Bovine)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50036863(N-{2-[(5-Methoxy-chroman-3-yl)-propyl-amino]-ethyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity towards dopamine receptor D1 in calf striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50036863(N-{2-[(5-Methoxy-chroman-3-yl)-propyl-amino]-ethyl...)
Affinity DataIC50: 500nMAssay Description:Binding affinity against D2 receptor in calf caudate nucleusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Bovine)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50036863(N-{2-[(5-Methoxy-chroman-3-yl)-propyl-amino]-ethyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor in calf frontal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50036863(N-{2-[(5-Methoxy-chroman-3-yl)-propyl-amino]-ethyl...)
Affinity DataIC50: 1.00E+6nMAssay Description:Binding affinity for 5-hydroxytryptamine 1B receptor in rat cortex, striatum and globus pallidusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Bovine)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50036863(N-{2-[(5-Methoxy-chroman-3-yl)-propyl-amino]-ethyl...)
Affinity DataIC50: 5.00E+4nMAssay Description:Binding affinity against alpha-2 adrenergic receptor in calf frontal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Bovine)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50036863(N-{2-[(5-Methoxy-chroman-3-yl)-propyl-amino]-ethyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity towards dopamine receptor D1 in calf striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50036863(N-{2-[(5-Methoxy-chroman-3-yl)-propyl-amino]-ethyl...)
Affinity DataIC50: 8nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A (5-HT1A) receptor in rat hippocampus membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Bovine)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50036863(N-{2-[(5-Methoxy-chroman-3-yl)-propyl-amino]-ethyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity against alpha-1 adrenergic receptor in calf frontal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50036863(N-{2-[(5-Methoxy-chroman-3-yl)-propyl-amino]-ethyl...)
Affinity DataKi:  1nMAssay Description:Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacementMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed