BDBM50036690 2-Cyano-3-[4-hydroxy-3-methoxy-5-(naphthalen-2-ylsulfanylmethyl)-phenyl]-acrylamide::CHEMBL330879

SMILES COc1cc(\C=C(/C#N)C(N)=O)cc(CSc2ccc3ccccc3c2)c1O

InChI Key InChIKey=PWAFUGMDLMAVBQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50036690   

TargetEpidermal growth factor receptor(Human)
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036690(2-Cyano-3-[4-hydroxy-3-methoxy-5-(naphthalen-2-yls...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of polyGAT phosphorylation by EGF receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036690(2-Cyano-3-[4-hydroxy-3-methoxy-5-(naphthalen-2-yls...)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibitory concentration against EGF receptor by polyGAT phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036690(2-Cyano-3-[4-hydroxy-3-methoxy-5-(naphthalen-2-yls...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HER-14 (human EGFR overexpressing NIH3T3) cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Human)
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036690(2-Cyano-3-[4-hydroxy-3-methoxy-5-(naphthalen-2-yls...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibitory concentration against ErbB2/neu (HER-2) by autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed