BDBM50036686 (E)-3-(3-Benzylsulfanylmethyl-4,5-dihydroxy-phenyl)-2-cyano-acrylamide::3-(3-Benzylsulfanylmethyl-4,5-dihydroxy-phenyl)-2-cyano-acrylamide::CHEMBL432428

SMILES NC(=O)C(=C\c1cc(O)c(O)c(CSCc2ccccc2)c1)\C#N

InChI Key InChIKey=JPNQHDIBDBJKGZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50036686   

TargetEpidermal growth factor receptor(Human)
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036686(3-(3-Benzylsulfanylmethyl-4,5-dihydroxy-phenyl)-2-...)
Affinity DataIC50: 940nMAssay Description:Inhibitory concentration against EGF receptor by polyGAT phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036686(3-(3-Benzylsulfanylmethyl-4,5-dihydroxy-phenyl)-2-...)
Affinity DataIC50: 640nMAssay Description:Inhibition of polyGAT phosphorylation by EGF receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036686(3-(3-Benzylsulfanylmethyl-4,5-dihydroxy-phenyl)-2-...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of HER-14 (human EGFR overexpressing NIH3T3) cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036686(3-(3-Benzylsulfanylmethyl-4,5-dihydroxy-phenyl)-2-...)
Affinity DataIC50: 646nMAssay Description:Inhibitory activity against epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
University of Tennessee Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50036686(3-(3-Benzylsulfanylmethyl-4,5-dihydroxy-phenyl)-2-...)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibitory activity tested against protein kinase HER-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Human)
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036686(3-(3-Benzylsulfanylmethyl-4,5-dihydroxy-phenyl)-2-...)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibitory concentration against ErbB2/neu (HER-2) by autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed