BDBM50036619 CHEMBL3354273

SMILES COc1ccc(CNc2nc(OCc3ccccn3)ncc2C(=O)N[C@H]2CC[C@H](O)CC2)cc1Cl

InChI Key InChIKey=NXJJDPAUDJRDIQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50036619   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Dog)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50036619(CHEMBL3354273)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of dog lungs PDE5 using [3H]cGMP as substrate after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed