BDBM50036542 CHEMBL3353600

SMILES CC(C)(C)c1ccc(CN(c2ncc(cc2Cl)C(F)(F)F)S(=O)(=O)c2ccc(cc2)C(O)=O)cc1

InChI Key InChIKey=PMMAWGLBEYFLAA-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50036542   

TargetTransient receptor potential cation channel subfamily M member 8(Human)
Raqualia Pharma

Curated by ChEMBL

LigandBDBM50036542(CHEMBL3353600)Copy SMILESCopy InChI

Affinity DataIC50: 0.960nMAssay Description:Antagonist activity at human TRPM8 expressed in HEK293 cells assessed as inhibition of menthol induced Ca2+ influxMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/15/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL